EMQ 8. Theme: The subcellular location of channels and carriers

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From the options below, identify the (final) subcellular location of the following carriers and channels.

A Endoplasmic reticulum
B Golgi complex
C Inner mitochondrial membrane
D Lysosome
E Outer mitochondrial membrane
F Peroxisome
G Plasma membrane

1. ATP synthase
Your Answer:
Answer: C, inner mitochondrial membrane. See figure 12.3 on book page 195.
2. cAMP-gated channel
Your Answer:
Answer: G, plasma membrane. see book page 258.
3. Connexon
Your Answer:
Answer: G, plasma membrane. see book page 46.
4.Inositol trisphosphate-gated calcium channel
Your Answer:
Answer A, endoplasmic reticulum. See book page 253.
5. Membrane attack complex
Your Answer:
Answer: G, plasma membrane. The membrane attack complex is assembled from components of complement during immune system attack on a target cell. See book page 317.
6. Porin
Your Answer:
Answer E, outer mitochondrial membrane. See book page 194.
7. Sodium/potassium ATPase
Your Answer:
Answer: G, plasma membrane. See book page 199.
8. Transporter associated with antigen processing (TAP)
Your Answer:
Answer A, endoplasmic reticulum. In vertebrates the TAP transports peptides from the cytosol into the endoplasmic reticulum, where they bind to major histocompatibility complex proteins for presentation at the cell surface. See book page 169.
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